What cancers cause cold urticaria?
Emily Wong
Updated on May 19, 2026
What cancers cause cold urticaria?
The most common cause of secondary acquired cold-induced urticaria is primary and secondary cryoglobulinemia (e.g. chronic lymphocytic leukemia, lymphosarcoma, leukocytoclastic vasculitis, hepatitis C virus infection, and angioimmunoblastic lymphadenopathy) based on case reports [23,24,25,26,27,28].
Can hives be linked to cancer?
In some cases, chronic hives may be related to an underlying illness, such as a thyroid disease or, rarely, cancer.
Why did I suddenly develop cold urticaria?
No one knows exactly what causes cold urticaria. Certain people appear to have very sensitive skin cells, due to an inherited trait, a virus or an illness. In the most common forms of this condition, cold triggers the release of histamine and other chemicals into the bloodstream.
Is cold urticaria an autoimmune disease?
Some forms of cold urticaria are also diseases of the autoimmune system. Autoimmune disorders are caused when the body’s natural defenses against “foreign” or invading organisms (e.g., antibodies) begin to attack healthy tissue for unknown reasons. Exposure of the skin to cold triggers symptoms of the disorder.
What autoimmune disease causes cold urticaria?
Familial cold urticaria is caused by mutations in the cold-induced autoinflammatory syndrome (NLRP-3) gene and is no longer classified as an inducible urticaria. In 1–5% of patients, cold urticaria is secondary to cryoproteins (mainly cryoglobulins).
Does cold urticaria ever go away?
In some people, cold urticaria goes away on its own after weeks or months. In others, it lasts longer. There is no cure for the condition, but treatment and preventive steps can help.
What cancers cause rashes?
Mycosis fungoides is a type of lymphoma—the most common form of blood cancer. When someone has mycosis fungoides, malignant cells in the blood travel to the skin. The most common mycosis fungoides symptoms causes lesions that appear as a scaly, itchy rash.
What cancers cause itching?
Itching is a common symptom of skin lymphoma, T-cell lymphoma, and Hodgkin’s lymphoma. Itching is less common in most types of non-Hodgkin’s lymphoma. The itching might be caused by chemicals released by the immune system in reaction to the lymphoma cells.
Is cold urticaria fatal?
Cold urticaria is potentially life-threatening with a risk of anaphylaxis and death on exposure of large areas to cold, for example jumping into cold water, hypothermia in neurosurgical and cardiothoracic operations.
Are skin cancers itchy?
Skin cancers often don’t cause bothersome symptoms until they have grown quite large. Then they may itch, bleed, or even hurt. But typically they can be seen or felt long before they reach this point.